New guidelines for histiocytosis clarify best practices for recently-defined cancers

The National Comprehensive Cancer Network (NCCN)—an alliance of leading cancer centers—today announced the publication of new NCCN Guidelines for Histiocytosis. Histiocytoses are rare disorders characterized by a buildup of white blood cells called histiocytes, which leads to tissue damage. This group of disorders is diagnosed in a few thousand people every year across the United […]

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Lung cancer cells have differential signaling responses to KRAS inhibitor treatment

Genetic alterations of the KRAS gene are some of the most common mutations in lung cancer patients, but unfortunately these patients have few effective treatment options. Drugs that target the G12C mutation in KRAS have shown some activity in lung cancer; however, alternative signaling pathways are often activated that bypass the KRAS inhibitor, resulting in […]

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